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Looking for Wise and Gano(ganoe,ganow)

I am a great granddaughter of Samuel William and Sarah Jane Smith Wise. My father and I have been looking for Samuels father Wm Wise. Samuels parents were Wm Wise and Elmira borden, he was born in Akron, Ohio. We are looking for William Gano who is Sarah's grandfather. Any leads would be greatly appreciated. the Gano's are from union county ohio but think he may have moved on to Indiana.