Ciampanella S from Arquata Del Tronto Ascioli Piceno Marche It Settling IN WV

I currently have three trees of Ciampanella's. They all came from the same region of Italy - two lines settled in Preston County and the other line settled in McDowell County. I am pretty sure they are all related but lack several pieces of the puzzle.

Line one: Lucia, Domenico, Domenica, and Sante - parents were Carmine Ciampanella and Beatrice DeSantis.
Line two: Edoard(Edward), Annibale, Loreto(Sorento) and Antonio - parents were Ferdinand Ciampanella and Annie - maiden name not known.
Line three: Arturio/Agostino and Benadetto - parents were Massimino Ciampanella and Jiutita Santolini and Antonio - parents were Massimino Ciampanella and unknown mother.

It makes me wonder if Carmine, Ferdinand and Massimino weren't brothers????

What I find odd is that the same families have all inter-married - Soccorsi, Ciampanella, Santolini, Marella, Lalli, and Lauri's. Again all from the same region of Italy.

Any and all help is greatly appreciated.