Early Travel on the Ohio River

I remember seeing a story of some people traveling by flatbottom boat
on the Ohio River from Pennsylvania,Maryland,and Virginia.Some of the
names I'm searching for are : SCOTT,McCLURE,PURCELL,DECKER,and DOUTHIT.These ancestors migrated to Ohio,Kentucky,Indiana and Illinois.My ancestor were making there way to Indiana in the early 1800's.
monsterpaul42