Kelley S of Southern Ohio

Hi! My name is Maggie. I've been working on my paternal grandmother's family history for a few months now. If I have my information correct, her grandmother was Margaret Kelley Casey, daughter of Dennis Kelley and Catherine McNamara. My best estimate says they came to America around 1850, with 2 children. I believe they lived in Glendale, Ohio or Springfield, Ohio, in the Cincinnati area. I think they had a rather large family, but after 1880 I can find no trace of them as a family unit.There are a lot of Kelleys out there, and if anyone is familiar with this branch, please contact me:)