Looking for the Ancestors and Parents of Francis a

Looking for the ancestors and parents of Francis A. Hart m1st Elizabeth Parker, he was born in KY about 1817/18, she was born in IN, in 1843 they were in Lexington, Fayette County KY, 1850 they were in Jackson County MO and by 1860 in Anderson County KS and by 1868 back in MO - this is my brickwall